CARBOXYMETHYL-STARCH EXCIPIENTS FOR GASTROINTESTINAL STABLE ORAL PROTEIN FORMULATIONS CONTAINING PROTEASE INHIBITORS

Carboxymethyl-Starch Excipients for Gastrointestinal Stable Oral Protein Formulations Containing Protease Inhibitors

Purpose.The aim of this study was to develop a formulation for bioactive compounds using Carboxymethyl Starch (CMS) as excipient containing protease inhibitors.This formulation provided gastro protection and enhanced stability against pancreatic enzymes.Such stability is needed for formulation of oral vaccines with specific antigens.Methods.CMS was

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An overview of the trypanosomatid (Kinetoplastida: Trypanosomatidae) parasites infecting several mammal species in Colombia

Abstract Background Trypanosomatids are among the most critical parasites for public health due to their impact on human, animal, and plant health.Diseases associated with these pathogens manifest mainly in poor and vulnerable populations, where social, environmental, and biological factors modulate the case incidence and geographical distribution.

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